ZIP Code 49221

49221 is one of Michigan's ZIP codes, delivering to addresses in Adrian, Lenawee County.

City: Adrian
County: Lenawee County
State: Michigan
Prefix: 492xx

Where this code sits

49221 is part of the 492xx range, the group of codes handled by one mail processing centre. It is the only ZIP code delivering to Adrian.

Adrian Michigan ZIP codes →

Area codes over the same ground

Postal and telephone geography are drawn separately, so these codes cover the area 49221 delivers to without sharing its boundary.

517 Area code 517

ZIP codes nearest 49221

The ZIP codes whose reference points sit closest to 49221.
ZIP code	Distance	Delivers to
ZIP code 49279	5.9 mi	Sand Creek, MI
ZIP code 49268	6.4 mi	Palmyra, MI
ZIP code 49286	8.0 mi	Tecumseh, MI
ZIP code 49235	9.1 mi	Clayton, MI
ZIP code 49248	9.3 mi	Jasper, MI
ZIP code 49287	9.6 mi	Tipton, MI
ZIP code 49289	9.7 mi	Weston, MI
ZIP code 49228	10 mi	Blissfield, MI

Straight-line distance between place reference points, not driving distance. Where a place has no Census Gazetteer point, its postal centroid is used instead.

Each point is the reference point for 49221, plotted from its record coordinates.

Reference points and footprint
Not an official NANPA boundary
Not a USPS delivery area

Scope ZIP code 49221. Source GeoNames US postal codes (2026-07 postal dump) and Census 2024 county Gazetteer (2024 Gazetteer). Updated 15 July 2026. A ZIP code is a set of delivery routes, not an area; the point shown is a record coordinate, not a centre.